Cannabis isn't just a plant—it's a 500-million-year evolutionary partnership between humans and one of nature's most sophisticated biochemical factories. These articles explore how cannabis works with our endocannabinoid system to enhance adaptation, reduce inflammation, and optimize the thermodynamic processes that keep us alive.
Dr. Bob Melamede spent decades studying the endocannabinoid system and its role in human health. His research revealed that cannabinoids aren't foreign substances that hijack our biology—they're molecules that work with systems our bodies evolved over millions of years. The endocannabinoid system regulates everything from mood and appetite to immune function and cellular repair.
These articles examine the science behind cannabis medicine, the politics that kept it illegal for decades, and the emerging research that's finally validating what traditional cultures knew for thousands of years. We explore how different cannabinoids affect the body, why the entourage effect matters, and how cannabis fits into a broader understanding of health as a far-from-equilibrium process.
Whether you're interested in cannabis for medical purposes, curious about the science behind its effects, or simply want to understand why this plant has been so controversial, these articles provide a thermodynamic perspective on one of nature's most remarkable medicines.
Charlotte Figi: The Girl Who Changed Everything
How one little girl with severe epilepsy transformed the conversation about cannabis medicine forever Insights from Dr. Bob Melamede's framework.
Pregnenolone: Your Body's THC Brake
Your body has a built-in mechanism to prevent THC overdose—a hormone that acts as a dimmer switch on CB1 activation Insights from Dr. Bob Melamede's framework.
The Hydrogen Peroxide + Cannabis Protocol
From Australian skin cancer cases: combining hydrogen peroxide with cannabis oil caused tumors to shrivel within one hour. The rationale: overwhelming cancer cells with free radicals.
The Citicoline Discovery: Modulating High-Dose Cannabis
Janet Sweeney discovered that citicoline can completely modulate the negative effects of high-dose cannabis, allowing therapeutic doses without overwhelming side effects.
The Stoner Stereotype is Dead
Let’s get one thing straight. The image of the lazy, giggling stoner with a bag of Doritos permanently attached to their hand is
Cannabis and the Adaptive Mind
You Think You're Relaxing, But You're Evolving Let’s get one thing straight. You’re not reading this because you want to lear
The Skillset Cannabis Unlocks
They told you it makes you lazy. They told you it makes you stupid. They sold you a load of bullshit about ambition and drive, a
Why Prohibition Makes No Scientific Sense
Let me ask you a question, and I want you to be brutally honest with yourself. Why does the United States government Insights from Dr. Bob Melamede's framework.
The Ultimate Bio-Hack
You’ve probably heard it all. The endless chatter about “bio-hacking” your way to a better life. Cold plunges that shock your system int
Cannabis Is Not a Drug
Let's get one thing straight. Everything you think you know about cannabis is probably wrong. You’ve been fed a steady diet of bullshit